A translucent complete human placental membrane allograft
Enverse is a translucent dehydrated complete human placental membrane allograftA tissue graft from a donor of the same species as the recipient but not genetically identical.1 optimized for use as a wound covering or barrier membrane. All three layers of the placental membrane tissue are preserved without disruption of the natural orientation during processing.2 Throughout the Clearify process, Enverse has been optimized to preserve extracellular matrix components, like collagens and glycoproteins, in a translucent, compact format.2
Product Features & Benefits
Why is Enverse unique?
The use of placental tissues in wound care has been documented in medical texts since the early 20th century.4 There are three distinct layers that make up this membrane: the amnion layerThe amnion layer is the innermost layer of the placental membrane. This layer provides tensile strength and acts as a fibrous skeleton.3, intermediate layerThe intermediate layer exists between the amnion and chorion layers and is rich in collagens, proteoglycans, and glycosaminoglycans, like hyaluronic acid.3, and chorion layerThe chorion layer is the outermost, thickest layer of the placental membrane. It contributes to elasticity and membrane stability.3.3 The three layers function together to create the ideal protective covering and barrier between the mother and the fetus.
While most placental membrane-based products provide single or dual layer allografts, StimLabs has developed the first membrane allograft to retain all three layers of the membrane, including the intermediate layer.2 The preserved intermediate layer is a vital part of the membrane barrier property intrinsic to the tissue. The layer contributes to the overall composition of the allograft, containing extracellular matrix components like collagenProvides strength and structural resistance to degrading enzymes in native placental tissue.4, proteoglycansPromotes tissue hydration in native placental tissue.4, and glycosaminoglycans, like hyaluronic acidProvides lubricating and elastic properties in native placental tissue.4.4
Where is Enverse commonly applied?
Specialties Include:
- Plastic Surgery
- Vascular Surgery
- General Surgery
- Infectious Disease
- Podiatry
- Orthopedics
- OB/GYN
- Urology
- Spine
How do we retain these components? 2
Clearify is a unique, patented technology for placental tissue that maximizes the retention of desired structural components, while effectively cleaning and terminally sterilizing the graft. Clearify is designed to preserve all three layers of the placental membrane. The Enverse allografts are oven-dried and never delaminated, meaning that in processing, the layers aren’t pulled apart. This protects the extracellular matrix components and the native architecture from being stripped away or damaged during processing.
Product Information
Sheet format | Shelf-stable for up to five (5) years
Sizes | 15 mm, 2x3 cm, 4x4 cm, 4x6 cm, 6x8 cm
Product Codes | EN-0015, EN-2030, EN-4040, EN-4060, EN-6080
For larger sizes, check out Revita® Burn Clear.
Product Information
Sheet format | Shelf-stable for up to five (5) years
Sizes | 10x10 cm
Product Codes | RU-1010
